Mesenchymal Tumors in Gastrointestinal Tract

Mesenchymal neoplasms arising in the digestive tract are rare compared to adenomas and carcinomas [1]. They include several entities with histomorphological similarity immunohistochemistry helps confirm diagnosis [2]. Our goals study epidemiological aspect of mesenchymal tumors, compare histological diagnoses before after use immunochemistry. This is a retrospective, descriptive, single-center performed on all cases tumors gastrointestinal tract, diagnosed at laboratory Pathological Anatomy Unit Joseph Ravoahangy Andrianavalona University Hospital from January 1, 2007 December 31, 2018. We included 29 cases. The mean age was 43.28 years. sex ratio 1.07. After immunohistochemical examination, 24.14% changed GISTs which most common tumor involving tract. In GIST should first be ruled out making other diagnoses. Histologic immunophenotypic features thereby essential. According literature review, if c-Kit DOG-1 negative, molecular biology must used.